Ep. 185 How to Make a Drug Pt 2: Libraries and Design

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Petri Dish

197 episodes

2 days ago

Profane, insane, and 100% primo science, Petri Dish is a no-BS podcast that explores the wildest subjects in modern science with clarity and evil joy. Hosted by Sean Allen, a Nanoparticle/Immunology Researcher, and Nathan Allen, his "screenwriter" brother, Petri Dish fuses hard science with a freewheeling and madcap conversational style. Cannabinoids, Plague, Cats, the dreaded Candiru, and the even more dreaded Covid-19: all these and more are dissected with intellect and irreverence, dropping every week. So reject ignorance. Join the Scientific Revolution. Join Petri Dish.

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Ep. 185 How to Make a Drug Pt 2: Libraries and Design

Petri Dish

58 minutes 55 seconds

1 year ago

Ep. 185 How to Make a Drug Pt 2: Libraries and Design

On this second episode about drug discovery, we discuss small molecule drug libraries and the challenges behind rational design! Don't know what that means? Tune in to find out!

References:

https://www.frontiersin.org/articles/10.3389/fcell.2019.00107/full

https://next.cancer.gov/discoveryresources/resources_ndl.htm

https://www.molbiolcell.org/doi/10.1091/mbc.E22-08-0377

https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapy-treatment-certain-patients-duchenne-muscular-dystrophy

https://www.goodrx.com/health-topic/gene-therapy/crispr-therapeutics-vertex-exa-cel

https://www.broadinstitute.org/what-broad/areas-focus/project-spotlight/crispr-timeline