At PA Mindset Matters, we shine a spotlight on exceptional PAs who are making a difference in mental health across all specialties. Our podcast and webinars are designed to connect and inspire the PA workforce—whether you’re a psych PA or a PA in primary care, emergency medicine, or any specialty—by providing practical insights and resources to integrate behavioral health into your practice. Together, we’re building a stronger, more connected community to raise each other up and deliver better patient care.
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At PA Mindset Matters, we shine a spotlight on exceptional PAs who are making a difference in mental health across all specialties. Our podcast and webinars are designed to connect and inspire the PA workforce—whether you’re a psych PA or a PA in primary care, emergency medicine, or any specialty—by providing practical insights and resources to integrate behavioral health into your practice. Together, we’re building a stronger, more connected community to raise each other up and deliver better patient care.
Navigating the Ketamine Landscape: History, Uses, and Myths I Mini Mindset Matters
PA Mindset Matters
26 minutes
3 weeks ago
Navigating the Ketamine Landscape: History, Uses, and Myths I Mini Mindset Matters
In this episode of The Mindset Matters Podcast, psychiatric PAs Mercedes Dodge and Jessica Spissinger dive into the fascinating journey of ketamine—from its origins as a battlefield anesthetic during the Vietnam War to its modern role as a rapid-acting antidepressant transforming mental health care. They unpack the differences between racemic ketamine and esketamine (Spravato®), discuss their use in treating depression, anxiety, PTSD, and chronic pain, and examine the evidence behind ketamine-assisted psychotherapy. The conversation explores how this once-controversial drug evolved from party stigma to clinical promise, highlighting mechanisms of action, dosing routes, safety considerations, side effects, and regulatory frameworks that guide its use today. You’ll also hear insights on combining ketamine with therapy to enhance long-term outcomes, myths and misconceptions, and what clinicians need to know before integrating ketamine into practice. Whether you’re a PA, clinician, or mental-health enthusiast, this episode offers a balanced, practical, and evidence-based look at one of psychiatry’s most exciting frontiers.
PA Mindset Matters
At PA Mindset Matters, we shine a spotlight on exceptional PAs who are making a difference in mental health across all specialties. Our podcast and webinars are designed to connect and inspire the PA workforce—whether you’re a psych PA or a PA in primary care, emergency medicine, or any specialty—by providing practical insights and resources to integrate behavioral health into your practice. Together, we’re building a stronger, more connected community to raise each other up and deliver better patient care.