The ATS (American Thoracic Society) International Conference is a key event in the global sleep and breathing health calendar. So in this episode of OnAir, we asked Kimberly Sterling and Luciana Rabello – who were there as part of ResMed’s Medical Affairs Team – to share the exciting developments and research findings that caught their attention. Topics discussed include: Endotypes: what they are and how they differ to phenotypes – with a look at the role endotyping can play in the management of heterogenous conditions like OSA, and why a collaborative approach to its application may be key. AI in medicine: how large-language models ‘think’ about complex care cases compared to the reasoning of seasoned clinicians, and the possibility of developing speech-based screening for sleep apnoea. GLP-1s: could the use of these anti-obesity medications be associated with increased PAP adherence? Kimberly and Luciana also tell us about connecting with peers to share scientific findings from the 26 abstracts ResMed supported at the event – including evidence that suggests PAP therapy reduces the risks of death and hospitalisation for patients with OSA.* Guests: Dr Kimberly Sterling - Vice President, Global Value & Access, Medical Affairs, ResMed Dr Luciana Rabello - Director of Clinical Advocacy, Medical Affairs, ResMed Host: Nina Wiklund is ResMed’s Global Medical Marketing Content Lead, and has a burning enthusiasm for clinical research. She is especially interested in the additional insights and possibilities real-world evidence can add to existing RCTs.  References and useful links: ATS President’s Message *A. Malhotra, J.-L. Pépin, P.A. Cistulli, A. Wimms, F. Lavergne, F.H. Sert Kuniyoshi, S.H. Munson, B. Schuler, S.R. Badikol, C. Wilson, L. Willes, C. Kelly, T. Kendzerska, D.A. Johnson, R. Heinzer, C.-H. Lee, A.V. Benjafield, and on behalf of the medXcloud group. All-cause Mortality in Obstructive Sleep Apnea: Systematic Literature Review Including Randomised Trials and Confounding Adjusted Non-randomised Controlled Studies and Meta-analysis of Positive Airway Pressure Treatment (abstract). Am J Respir Crit Care Med 2024;209:A4735. The podcast OnAir, with Clinical Respiratory News (CRN) is a medical education non-promotional for healthcare professionals organised by ResMed. Learn more at https://webinars.resmed.eu/podcasts-list/. This podcast is intended for healthcare professionals only. Disclaimer: This programme is non promotional and is sponsored by ResMed. The content contained in this programme was jointly developed by the speakers and ResMed, and is not eligible for continuing medical education (CME) credits. Listen to OnAir with Clinical Respiratory News, the podcast that brings you fresh insights and thought-provoking discussions about hot topics in sleep and breathing health. © ResMed