Loong Wang is the CEO and Co-Founder of QDX, a company specializing in computational drug discovery using quantum mechanics and supercomputing. In this episode, Loong discusses his journey from supercomputing at the Australian National University to founding multiple startups in distributed computing and blockchain—before making a significant pivot to biotechnology. His deep dive into quantum chemistry aims to address complex drug discovery challenges by simulating atomic and molecular behaviors at a fundamental level. He also touches on the potential for quantum chemistry to revolutionize high-throughput screening methods that big pharmaceutical companies currently rely on, making these processes faster, cheaper, and more precise. He emphasizes understanding the nuances of biomedical problems and the need for a multidisciplinary approach in developing groundbreaking solutions.

Host: John Joson Ng Editors: Jessie Wong, John Joson Ng

The show notes and transcripts for the episode can be found on nucleatesingapore.substack.com. For feedback or recommendations on who we should talk to next, please reach out to Joson Ng via johnjoson.n@nucleate.org.

01:02 - Introduction 06:16 - Understanding Quantum Mechanics in Drug Discovery 18:53 - Challenges in Biotech: Collaboration and Simulations 26:30 - Entrepreneurship, IP Strategy, and Scaling Up 42:22 - Advice for Non-Traditional Entrants to Biotech