In the wake of the COVID-19 pandemic, the need to trust AI in global health has become increasingly important. As we navigate global challenges such as poverty, conflict, and societal polarization, trust in AI and its role in health management is under scrutiny. This panel explores AI's potential to enhance global public health, improve crisis preparedness, and combat misinformation. Key questions include: Can AI truly support the common good without human oversight? How can we balance technological progress with preserving essential human values? Beyond the health sector, trust in AI is essential for its broader adoption. Health, as a key application area, highlights the need to build and maintain public trust to ensure AI's positive impact. This discussion focusses on the ethical frameworks needed to guarantee AI's beneficial role, while preserving public trust and human dignity in global health initiatives.