The war in Gaza triggered by Hamas’ attacks on Israel in October 2023 sparked several massive aftershocks that have redrawn the geopolitical map of the Middle East. After decimating Hamas, the Israel Defense Forces went on to effectively neuter Hezbollah in Lebanon, depriving Iran of its most potent forward threat to Israel. The overthrow of the Assad regime in Syria last December further weakened the so-called Axis of Resistance. With Iran at its most vulnerable in decades, Israel took the fight to the Islamic Republic in a 12-day offensive in June that left its chief regional foe reeling. The aftermath of the violence has significantly altered the balance of power in the Middle East. Israel has emerged as the primary security power in the region, Iran has seen its influence evaporate, and other countries are calibrating their responses to the new reality. How do Arab states, particularly those in the Gulf, which have only recently moved to détente with Iran, respond to Israel’s rise in tandem? The Middle East Institute’s Annual Conference 2025 unpacked the effects of a re-ordered region on the rest of the world via three panels staffed with experts. These panels examined the impact of the far-reaching changes brought about by almost two years of war. Mr K Shanmugam, Coordinating Minister for National Security and Minister for Home Affairs, opened the conference.