In this episode, we're joined by Dr. Richard Menzies and Dr. Jonathan Campbell from the McGill Respiratory Epidemiology and Clinical Research Unit to discuss the results of their multi-center RCT comparing 4 months of rifampin to 9 months of isoniazid for the treatment of latent TB. Their findings are outlined in two papers, entitled "Four Months of Rifampin or Nine Months of Isoniazid for Latent TB in Adults" and "Safety and Side Effects of Rifampin Versus Isoniazid in Children" published in the August 2018 issue of the New England Journal of Medicine.
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In this episode, we're joined by Dr. Richard Menzies and Dr. Jonathan Campbell from the McGill Respiratory Epidemiology and Clinical Research Unit to discuss the results of their multi-center RCT comparing 4 months of rifampin to 9 months of isoniazid for the treatment of latent TB. Their findings are outlined in two papers, entitled "Four Months of Rifampin or Nine Months of Isoniazid for Latent TB in Adults" and "Safety and Side Effects of Rifampin Versus Isoniazid in Children" published in the August 2018 issue of the New England Journal of Medicine.
Episode 1 - Paul Savage - A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer
Mcgill University Medical Podcast Series
20 minutes 20 seconds
7 years ago
Episode 1 - Paul Savage - A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer
Paul Savage is an MD-PhD student in the lab of Dr. Morag Park at the Goodman Cancer Research Centre in Montreal, Canada. In this episode, we discuss his latest article published in the October 2017 edition of Cell Reports. Using a patient-derived xenograft model to screen triple negative breast cancer (TNBC) tumours for susceptibility to targeted therapies, he and his colleagues identified an exceptional responder to treatment with the epidermal growth factor receptor (EGFR) inhibitor gefitinib. Single-cell RNA sequencing and functional assays were used to characterize a new tumour-initiating program within this exceptional responder, which may represent a new target in the treatment of a subset of TNBC patients.
Mcgill University Medical Podcast Series
In this episode, we're joined by Dr. Richard Menzies and Dr. Jonathan Campbell from the McGill Respiratory Epidemiology and Clinical Research Unit to discuss the results of their multi-center RCT comparing 4 months of rifampin to 9 months of isoniazid for the treatment of latent TB. Their findings are outlined in two papers, entitled "Four Months of Rifampin or Nine Months of Isoniazid for Latent TB in Adults" and "Safety and Side Effects of Rifampin Versus Isoniazid in Children" published in the August 2018 issue of the New England Journal of Medicine.
