In this episode we spoke with Dr. Lori Ploutz-snyder about how to exercise during spaceflight missions. Dr. Ploutz-snyder is a professor of Movement Science and the Dean of the University of Michigan School of Kinesiology. Previously, she was the Lead Scientist for the Exercise Physiology and Countermeasures Project at the NASA Johnson Space Center in Houston. Her research focuses on studying how to counteract the negative effects of unloading on muscle and bone physiology that occur during spaceflights and how to use this information to create countermeasures to protect the well-being of astronauts. During our conversation we talk about how and why our bodies change during spaceflights, how long these changes last after space missions and if some of these changes can be irreversible. We talk about using exercise as a countermeasure to maintain the health of crew members during these long-term missions and the main challenges that we encounter when we need to design training interventions for people while they are in the space. This and much more in a fascinating conversation that I hope you will enjoy. Dr. Ploutz-snyder's research can be followed at https://www.kines.umich.edu/directory/lori-ploutz-snyder.