In this Master USMLE episode, we explore the high-yield clinical consequences of thiazide diuretics like chlorthalidone. Learn how these commonly prescribed medications can cause serious metabolic shifts—often missed on Step 2 CK questions.

We break down:
– Why thiazides cause hyperglycemia and worsen insulin resistance
– How they elevate uric acid levels and trigger gout
– The key electrolyte changes: low potassium, low magnesium, high calcium
– Which patients are at greatest risk for complications
– What exam traps to avoid and how to reason through them

Built around real-life clinical reasoning, this episode strengthens your test-day strategy and your clinical instincts.

Follow the Master USMLE podcast for more high-yield, case-based reviews to help you study smarter and score higher.