Despite common misconceptions, lupus nephritis is part of a broader immune imbalance seen in systemic lupus, not a separate condition. This is why it's important to shift focus from organ-specific treatment to immune dysregulation targeting. Hear Dr. Joan Merrill, Professor at the Oklahoma Medical Research Foundation’s Arthritis and Clinical Immunology Research Program in Oklahoma City, discuss the spectrum of lupus and, based on that, considerations for treatment. Dr. Merrill also presented on this topic at the 2025 Congress of Clinical Rheumatology West conference.