In this episode of Intermediate Med-Surg, we dive into Chapter 51 of Lewis’s Medical-Surgical Nursing to explore the full spectrum of renal failure—acute kidney injury (AKI) and chronic kidney disease (CKD). We’ll walk through the differences in onset, progression, and outcomes; review RIFLE criteria; and highlight essential nursing responsibilities across phases of care. From electrolyte imbalances to dialysis to transplant considerations, this chapter lays the foundation for understanding kidney function and its critical role in patient health. Perfect for anyone reviewing elimination, acid-base balance, or preparing for renal-focused care planning.