In this episode, we wrap up our heart failure series with a practical, case-based discussion. Building on the foundation of diagnostics, fluid management, and guideline-directed medical therapy covered in earlier episodes, we bring it all together by working through real-world patient scenarios. We explore: Case 1: A new diagnosis of HFrEF in a patient with multiple comorbidities. Case 2: Medication optimization in a patient with chronic HFrEF and CKD. Case 3: Managing HFpEF with suboptimal volume status. Case 4: An acute decompensated heart failure exacerbation with critical management decisions. This case-focused discussion highlights the stepwise approach to diagnosis, optimization of GDMT, and the importance of tailoring treatment to each patient’s comorbidities, lifestyle, and access to care. Whether you’re managing heart failure in the hospital, clinic, or home setting, this episode brings the series full circle with practical insights you can apply directly to patient care.   Learn more about Key Medical Care