In this fifth installment of our Heart Failure series, we dive deep into one of the core pillars of guideline-directed medical therapy (GDMT) for patients with HFrEF: Beta Blockers. You’ll learn: How beta-1, beta-2, and beta-3 adrenergic receptors work Why slowing the heart rate helps in HFrEF The evidence-based beta blockers for HFrEF (and their dosing) Common pitfalls in prescribing, like confusing metoprolol tartrate vs. succinate When to avoid beta blockers—and how to safely use them in patients with COPD or asthma This episode is packed with pearls for clinicians working in geriatrics, primary care, and cardiology. Whether you're managing patients in the SNF, in the home, or via telemedicine, this practical review will help you optimize outcomes for patients with heart failure.