Yiannis Chatzizisis, Maryam Alsharqi, Evan Shlofmitz, Daniel Chamié discuss three important papers published in the JSCAI special issue. The panel explores advancements in intravascular imaging (IVI) technologies, the latest research, the current landscape of AI applications, and the educational needs to bridge practice gaps. The discussion highlights how AI-driven tools can be leveraged for PCI planning, including lesion assessment, procedural optimization, and workflow efficiency to enhance patient outcomes.1- Artificial Intelligence in Cardiovascular Imaging and Interventional Cardiology: Emerging Trends and Clinical Implications: https://doi.org/10.1016/j.jscai.2024.1025582- Artificial Intelligence in Intravascular Imaging for Percutaneous Coronary Interventions: A New Era of Precision: https://doi.org/10.1016/j.jscai.2024.102506 3-Can AI Capture and Quantify Clinical Expertise? Implications for Intracoronary Imaging in Percutaneous Coronary Intervention: https://doi.org/10.1016/j.jscai.2024.102523Read the issue: https://www.jscai.org/issue/S2772-9303(25)X0003-X