This episode discusses a multi-institutional study evaluating the impact of bevacizumab in frontline chemotherapy for advanced ovarian clear cell carcinoma. Researchers analyzed data from 178 patients treated between 2008 and 2018 and found that adding bevacizumab significantly improved progression-free and overall survival. Patients who received bevacizumab had a median progression-free survival of 29.7 months compared to 10.5 months in those who did not. Median overall survival was 51.4 months versus 27.4 months. These findings suggest that bevacizumab may be an effective addition to first-line treatment for this rare and chemoresistant ovarian cancer. Tune in to learn more about the study and its clinical implications.

Bevacizumab in frontline chemotherapy improved the survival outcome for advanced ovarian clear cell carcinoma: A multicenter retrospective analysis