In this episode of the JGO podcast, we delve into a cost-effectiveness analysis from the SHAPE trial, comparing simple hysterectomy to radical hysterectomy for patients with low-risk early-stage cervical cancer. The study, led by Dr. Janice S. Kwon and published in November 2024, found that simple hysterectomy was both more effective and less costly, with an average cost savings of 1,511 Canadian dollars per patient and improved quality-adjusted life expectancy. Postoperative complications, including urinary incontinence and retention, were significantly lower with simple hysterectomy, and recurrence-free survival rates were comparable between the two procedures. These findings strongly support simple hysterectomy as the new standard of care, offering better patient outcomes and reduced healthcare costs. Tune in to learn more about how this study could transform global treatment practices.

Cost-effectiveness analysis of simple hysterectomy compared to radical hysterectomy for early cervical cancer (https://doi.org/10.3802/jgo.2024.35.e117)