On March 11th, 2020 the World Health Organization declared the COVID-19 infection a pandemic. We are currently in the throws of that global infection and the big question everyone is racing to ask and answer is the risk of ischemic stroke higher in patients with COVID-19 infection. We spoke to both Drs based in the United States Adnan Quereshi from the University of Missouri, Department of Neurology, and Vishal Jani from the Creighton University School of Medicine, Immanuel Medical Centre Omaha Nebraska, who is the corresponding author for the article “Management of Acute Ischemic Stroke in Patients with COVID-19 Infection: Report of an International Panel” This important paper is from a team of doctors on the front line from the USA, Egypt, Turkey, Iran, Italy Taiwan, Pakistan, Poland, France and China and more presents a comprehensive set of practice implications in a single document for clinicians caring for adult patients with acute ischemic stroke with confirmed or suspected COVID-19 infection.