Chances are when we’re treated with medicines in hospital or pick up our prescriptions at the pharmacy, we don’t give much thought about how the drugs that are so vital for our health and wellbeing came to be. The fact is the journey that a new medicine takes from its beginnings in the laboratory to finally being administered to patients can be long and arduous. It typically takes the work of countless scientists, researchers and technologists toiling away behind the scenes for decades and is often fraught with failure. So exactly how does a new drug make the grade? In this episode, we’re joined by oncologist and drug researcher Dr William Pao to talk about his latest book, Breakthrough – The Quest for Life-Changing Medicines. He tells us how fundamental academic scientific lays down the bedrock for the development of a new drug, runs us through the vital importance that clinical trials play in the whole drug development process, and tells us the fascinating story of how the common everyday drug paracetamol was discovered by accident. Learn more about your ad choices. Visit podcastchoices.com/adchoices