Conversations with the brightest, most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and much more.
All content for Inside Matters is the property of Dr James McIlroy and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Conversations with the brightest, most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and much more.
Decoding the Microbiome: Genetic Discoveries with Dr. Ran Blekhman
Inside Matters
1 hour 5 minutes 23 seconds
4 months ago
Decoding the Microbiome: Genetic Discoveries with Dr. Ran Blekhman
In this episode, Dr. James McIlroy interviews Dr. Ran Blekhman, an associate professor at the University of Chicago, about the microbiome and its role as 'our second genome.'
Dr. Blekhman shares his research findings on the genetic and environmental factors that shape the microbiome, the heritability of microbial genes, and the relationship between the human genome and microbiome. They also discuss Dr. Blekhman's groundbreaking research that analysed over 168,000 samples to understand global microbiome patterns, the influence of early-life microbiome development, and the potential of microbiome-based diagnostics and therapeutics. Tune in for a comprehensive dive into one of the most promising areas of genetic and microbial research.
00:00 Introduction to Dr. R Blackman and the Microbiome01:23 Podcast Growth and Listener Engagement01:56 Starting the Conversation with Dr. Blackman02:04 Exploring the Second Genome02:24 Human Genome vs. Microbiome03:23 Genetic Interactions with the Microbiome04:02 Understanding Microbial Genes and Functions05:40 Heritability and Environmental Factors06:53 Microbiome Diversity and Heritability08:57 Research on Microbiome Heritability17:18 Baboon Model System for Microbiome Studies18:56 Population Scale Microbiome Research25:27 Global Patterns and Data Integration33:36 The Untapped Potential of Microbiome Data35:08 Hypotheses and Discoveries in Microbiome Research36:46 Geographical Variations in Microbiome49:18 Technical Challenges and Methodologies52:20 AI and Machine Learning in Microbiome Studies54:59 Future Directions and Clinical Applications01:00:38 Exploring Early Life Microbiome01:03:30 Conclusion and Further Reading
Inside Matters
Conversations with the brightest, most forward-thinking minds in health, fitness, science, nutrition and business. In-depth discussions about how our gut microbiome impacts our health, well-being, mood and much more.
