Professor Chris O'Callaghan tells us about the role of our immune system in vascular disease. The accumulation of fat in the arteries, such as cholesterol, can cause a thickening of the artery wall known as atherosclerosis. Professor Chris O'Callaghan is researching the role of the innate immune system in atherosclerosis to better understand immune responses to vascular disease. This may lead to improved treatments. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
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Professor Chris O'Callaghan tells us about the role of our immune system in vascular disease. The accumulation of fat in the arteries, such as cholesterol, can cause a thickening of the artery wall known as atherosclerosis. Professor Chris O'Callaghan is researching the role of the innate immune system in atherosclerosis to better understand immune responses to vascular disease. This may lead to improved treatments. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
Dr Hal Drakesmith tells us how his work on iron availability can help us fight infections. Iron plays essential biochemical roles in oxygen binding, ATP synthesis and DNA metabolism. It also influences infection outcomes, since pathogens can resist the immune system when iron availability is high, leading to rapid infection. The level of iron available in different tissues is controlled by the small peptide hormone hepcidin. Dr Hal Drakesmith is investigating how hepcidin is modulated during infection to identify new ways of combating infectious diseases such as HIV, malaria and Hepatitis C. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
Immunology
Professor Chris O'Callaghan tells us about the role of our immune system in vascular disease. The accumulation of fat in the arteries, such as cholesterol, can cause a thickening of the artery wall known as atherosclerosis. Professor Chris O'Callaghan is researching the role of the innate immune system in atherosclerosis to better understand immune responses to vascular disease. This may lead to improved treatments. Creative Commons Attribution-Non-Commercial-Share Alike 2.0 UK: England & Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/
