Join Jack McDonnell, MD, a pediatric immunologist and assistant professor at Cleveland Clinic Lerner College of Medicine, and Elie Haddad, MD, PhD, a clinician-researcher in pediatric immunology, full professor at the University of Montreal, and head of the Immunology and Rheumatology department at CHU Sainte-Justine, as they explore the evolving world of immune deficiency and dysregulation.
Presented by the Primary Immune Deficiency Treatment Consortium (PIDTC), this podcast features conversations with leading experts, pioneering researchers, patients, and advocacy groups. Each episode uncovers cutting-edge research, clinical challenges, and personal stories—ensuring that the patient voice remains at the center of the discussion.
Whether you're a clinician, researcher, patient, or advocate, Immune Matters brings you the latest insights in diagnosis, treatment, and innovation in primary immune disorders.
Tune in to explore the science, the stories, and the future of immune health.
The Primary Immune Deficiency Treatment Consortium (PIDTC) is a part of the Rare Diseases Clinical Research Network of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH).
This work was supported by the Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases (DAIT, NIAID) and the ORDR under cooperative agreements U54-AI082973 and U54-NS064808 and grants R13-AI094943 and 1R24AI184316-01.
The content and opinions expressed are solely the responsibility of the authors and do not represent the official policy or position of the NIAID, ORDR, NCATS, NIH, HRSA, or any other agency of the US Government.
All content for Immune Matters: a PIDTC Podcast is the property of Jack McDonnell and is served directly from their servers
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Join Jack McDonnell, MD, a pediatric immunologist and assistant professor at Cleveland Clinic Lerner College of Medicine, and Elie Haddad, MD, PhD, a clinician-researcher in pediatric immunology, full professor at the University of Montreal, and head of the Immunology and Rheumatology department at CHU Sainte-Justine, as they explore the evolving world of immune deficiency and dysregulation.
Presented by the Primary Immune Deficiency Treatment Consortium (PIDTC), this podcast features conversations with leading experts, pioneering researchers, patients, and advocacy groups. Each episode uncovers cutting-edge research, clinical challenges, and personal stories—ensuring that the patient voice remains at the center of the discussion.
Whether you're a clinician, researcher, patient, or advocate, Immune Matters brings you the latest insights in diagnosis, treatment, and innovation in primary immune disorders.
Tune in to explore the science, the stories, and the future of immune health.
The Primary Immune Deficiency Treatment Consortium (PIDTC) is a part of the Rare Diseases Clinical Research Network of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH).
This work was supported by the Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases (DAIT, NIAID) and the ORDR under cooperative agreements U54-AI082973 and U54-NS064808 and grants R13-AI094943 and 1R24AI184316-01.
The content and opinions expressed are solely the responsibility of the authors and do not represent the official policy or position of the NIAID, ORDR, NCATS, NIH, HRSA, or any other agency of the US Government.
In this episode, Dr. Jennifer Leiding, a pediatric clinical immunologist, discusses Chronic Granulomatous Disease (CGD) with Jack and Elie. CGD is an inherited immune deficiency that leads to severe infections and autoimmunity. She explains the dual nature of immune deficiency and autoimmunity in CGD patients, the role of transplantation as a treatment option, and the expectations for families receiving a CGD diagnosis. Dr. Leiding also shares insights from her research on CGD, the complexities surrounding the concept of a cure, and the emotional burden faced by families. The conversation touches on the potential of gene therapy as an experimental treatment and highlights the often-overlooked symptoms experienced by carrier mothers of X-linked CGD. Overall, the episode provides a comprehensive overview of CGD, its challenges, and the ongoing efforts to improve patient outcomes.
The Primary Immune Deficiency Treatment Consortium (PIDTC) is a part of the Rare Diseases Clinical Research Network of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH).
This work was supported by the Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases (DAIT, NIAID) and the ORDR under cooperative agreements U54-AI082973 and U54-NS064808 and grants R13-AI094943 and 1R24AI184316-01.
The content and opinions expressed are solely the responsibility of the authors and do not represent the official policy or position of the NIAID, ORDR, NCATS, NIH, HRSA, or any other agency of the US Government.
Keywords: Chronic Granulomatous Disease, CGD, immune deficiency, transplantation, gene therapy, pediatric immunology, autoimmune disease, PIDTC, patient care, immunology
Immune Matters: a PIDTC Podcast
Join Jack McDonnell, MD, a pediatric immunologist and assistant professor at Cleveland Clinic Lerner College of Medicine, and Elie Haddad, MD, PhD, a clinician-researcher in pediatric immunology, full professor at the University of Montreal, and head of the Immunology and Rheumatology department at CHU Sainte-Justine, as they explore the evolving world of immune deficiency and dysregulation.
Presented by the Primary Immune Deficiency Treatment Consortium (PIDTC), this podcast features conversations with leading experts, pioneering researchers, patients, and advocacy groups. Each episode uncovers cutting-edge research, clinical challenges, and personal stories—ensuring that the patient voice remains at the center of the discussion.
Whether you're a clinician, researcher, patient, or advocate, Immune Matters brings you the latest insights in diagnosis, treatment, and innovation in primary immune disorders.
Tune in to explore the science, the stories, and the future of immune health.
The Primary Immune Deficiency Treatment Consortium (PIDTC) is a part of the Rare Diseases Clinical Research Network of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH).
This work was supported by the Division of Allergy, Immunology and Transplantation, National Institute of Allergy and Infectious Diseases (DAIT, NIAID) and the ORDR under cooperative agreements U54-AI082973 and U54-NS064808 and grants R13-AI094943 and 1R24AI184316-01.
The content and opinions expressed are solely the responsibility of the authors and do not represent the official policy or position of the NIAID, ORDR, NCATS, NIH, HRSA, or any other agency of the US Government.
