Journal-Clubbing Our Way Through Internal Medicine
Do you also find it hard to follow the medical literature?
Newsletters with tables of contents are hard to get through after having written all your notes and maybe having done a chart dissection.
Welcome to IM Journal Club!
Our mission: to guide you through some of the most interesting internal medicine studies published in the last few weeks and months that you WOULD have liked to or SHOULD have heard about
Target groups: physicians and other clinicians in general internal or family medicine – hospital medicine and primary care – or in an internal medicine subspecialty; biostatisticians, epidemiologists, or data scientists; journal club enthusiasts!
Hidden agenda: to shed some lights on the studies’ methods AND on the context (what was known before, how do the new results change things – so what does this all mean?). We will give you episodes with primers on particularly difficult methods.
We will come out with a new episode every one to two weeks - we'll upload early on Fridays - so you can listen on your commute or on the weekend.
Please subscribe in your favorite podcast app or to our YouTube channel .
Please let us know what we can do better, or what new study we could cover: You can leave a review in your podcasting app, a comment on YouTube, or drop us a line at hello@imjournalclub.com
We are also on social; our email newsletter will be on Twitter: https://twitter.com/IMJournalClub
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Show Credits
Host: Ben Geisler
Video editor: Fernando Tábora
Methods consultant: Professor Ulrich Mansmann
Advisory group (current): Bijay Acharya, Chang-Berm Kang, Jeffrey L. Greenwald, Jonathan W. Heflin, Kathy May Tran, Marcel Müller, Rahul Ganatra, and Warren Chuang
Supported by LMU Munich’s Institute for Epidemiology, Biometry, and Medical Information Processing
Hosted on Acast. See acast.com/privacy for more information.
Journal-Clubbing Our Way Through Internal Medicine
Do you also find it hard to follow the medical literature?
Newsletters with tables of contents are hard to get through after having written all your notes and maybe having done a chart dissection.
Welcome to IM Journal Club!
Our mission: to guide you through some of the most interesting internal medicine studies published in the last few weeks and months that you WOULD have liked to or SHOULD have heard about
Target groups: physicians and other clinicians in general internal or family medicine – hospital medicine and primary care – or in an internal medicine subspecialty; biostatisticians, epidemiologists, or data scientists; journal club enthusiasts!
Hidden agenda: to shed some lights on the studies’ methods AND on the context (what was known before, how do the new results change things – so what does this all mean?). We will give you episodes with primers on particularly difficult methods.
We will come out with a new episode every one to two weeks - we'll upload early on Fridays - so you can listen on your commute or on the weekend.
Please subscribe in your favorite podcast app or to our YouTube channel .
Please let us know what we can do better, or what new study we could cover: You can leave a review in your podcasting app, a comment on YouTube, or drop us a line at hello@imjournalclub.com
We are also on social; our email newsletter will be on Twitter: https://twitter.com/IMJournalClub
---
Show Credits
Host: Ben Geisler
Video editor: Fernando Tábora
Methods consultant: Professor Ulrich Mansmann
Advisory group (current): Bijay Acharya, Chang-Berm Kang, Jeffrey L. Greenwald, Jonathan W. Heflin, Kathy May Tran, Marcel Müller, Rahul Ganatra, and Warren Chuang
Supported by LMU Munich’s Institute for Epidemiology, Biometry, and Medical Information Processing
Hosted on Acast. See acast.com/privacy for more information.
How Do COVID Vaccines Work If You’re Immunocompromised? In our second journal club, we look at one of those subgroups of patients that require our special attention - not children or pregnant women, but the immunocompromised. In addition to other aspects of this important topic, we address the following questions:
- What immune responses do various COVID vaccines elicit in them?
- Does the reason why you are immunocompromised make a difference?
- Are there even differences, if small, between the different vaccines?
- What assays should be used if we cannot just rely on small numbers of breakthrough infections as a study endpoint?
- Finally, what are the CDC's current recommendation for this group of patients?
0:00 Intro
1:26 CDC Guidelines for the Immunocompromised
8:14 Background: Immunocompromise and COVID-19
9:21 Study Goals
9:42 Methods
15:25 Baseline Characteristics
17:04 Results
29:23 Summary of the Main Findings
31:16 Limitations
33:00 Discussion
36:28 Outro
Ref: Haidar G et al. Prospective evaluation of COVID-19 vaccine responses across a broad spectrum of immunocompromising conditions: the COVICS study. Clin Infect Dis. 2022 Feb 18;ciac103. doi: 10.1093/cid/ciac103. Online early.
https://pubmed.ncbi.nlm.nih.gov/35179197/
Speakers: Elaine Tennant, MRCP-UK, DTHM, MPHTM, FRACP and Camille N. Kotton, MD, FIDSA, FAST
Host: Ben Geisler
Video editor: Fernando Tábora
Date of recording: March 17, 2022
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Hosted on Acast. See acast.com/privacy for more information.