In this episode of the IJGC podcast, Editor-in-Chief Dr. Pedro Ramirez, is joined by Drs. Ilaria Capasso, Camilla Nero, and Evelyn A. Reynolds to discuss ctDNA in Endometrial Cancer . Dr. Capasso completed her OBGYN residency at Fondazione Policlinico Agostino Gemelli (Rome, Italy), where she worked in the Gynecologic Oncology Unit with a focus on clinical and translational research in endometrial cancer. From May 2022 to May 2023, she was a Visiting Research Fellow at Mayo Clinic (Rochester, MN, USA), leading projects on AI, the microbiome, and ctDNA in endometrial cancer. She is currently a consultant in the Gynecologic Oncology Unit at Gemelli and continues to collaborate with Mayo Clinic as a research collaborator. Camilla Nero, MD, PhD, is a clinician-scientist in the Division of Gynecologic Oncology at Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, where her translational work focuses on gynecological cancers. She has authored key studies on dual CDK12/13 inhibition in patient-derived ovarian cancer organoids and numerous reviews on treatment resistance and novel therapeutic strategies. In 2024, she was awarded the AIRC Next Gen Clinician Scientist Grant to support her independent research in gynecological cancers at Gemelli. Evelyn A. Reynolds, M.D., is a board-certified Gynecologic Oncologist specializing in surgical care for women with gynecologic cancers. She has hed faculty positions at the University of Kansas and Morehouse School of Medicine. Since returning to Mayo Clinic in 2023, she has also expanded her academic role, focusing her research on the early detection of endometrial cancer, optimizing surgical outcomes and reducing healthcare disparities.