Dr. Russell Sharp discusses recent research (published in npj Microgravity) showing that lettuce grown on the International Space Station contains significantly less calcium and magnesium and lower antioxidant and protective compounds than Earth-grown counterparts. These nutrient changes matter for astronauts who already face bone loss, radiation stress, and digestive changes in space. The episode explores possible causes (microgravity, humidity, lighting, fertiliser), solutions such as biofortification, bioengineering, and choosing flavonoid-rich or seed/legume crops like soybeans, and outlines future research directions for producing nutritionally adequate crops on long-duration space missions. https://eutrema.co.uk/shop/fertiliser/liquid-gold-unique-complete-fertiliser/   Tim Peake, Helen Sharman, Neil Armstrong, Sally Ride, Yuri Gagarin, John Glenn, Buzz Aldrin, Valentina Tereshkova, Blue Origin, SpaceX, Elon Mush, Jeff Bezos, Heinlein, Isaac Asimov, Arthur C. Clarke, Star Trek