The genetic revolution in treating neurodegenerative disease with Martin Jacko

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Human 3 with Brom and Sam

Brom Rector and Sam Tabone

32 episodes

6 days ago

Interviews with the scientists, founders and investors driving Human 3 - the next epoch of health, wellbeing and performance. Topics include brain-computer interfaces, genetic medicine, psychedelics, longevity, AI and more. Hosted by Brom Rector and Sam Tabone - founders of XEIA Venture Partners, a venture capital fund investing in Human 3. More at www.xeiavp.com

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The genetic revolution in treating neurodegenerative disease with Martin Jacko

Human 3 with Brom and Sam

1 hour 5 minutes 6 seconds

4 months ago

The genetic revolution in treating neurodegenerative disease with Martin Jacko

Martin Jacko is the founder of Aperture Therapeutics, a startup developing ASO (Antisense Oligonucleotide) based therapies for neurodegenerative diseases like ALS. Aperture's approach is unique in how they are guided by genetic profiles of individuals who are naturally resilient to neurodegenerative diseases. Martin joins Sam Tabone and Brom Rector to discuss (5:00) - Aperture origin story

(10:00) - history of trying to cure ALS, why 150 attempts failed

(25:00) - why neuro is hot right now - genetic medicine

(33:00) - why 23 and me failed

(41:00) - how genetics lead to personalized medicine

(53:00) - martin’s advice for founders https://www.aperturetx.com/