The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017.
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.
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The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017.
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.
Male vs. Female Brain Differences & How They Arise From Genes & Hormones | Dr. Nirao Shah
Huberman Lab
2 hours 26 minutes
1 month ago
Male vs. Female Brain Differences & How They Arise From Genes & Hormones | Dr. Nirao Shah
My guest is Dr. Nirao Shah, MD, PhD, a professor of psychiatry, behavioral sciences and neurobiology at Stanford University School of Medicine. We discuss how the brains of males and females differ and how those differences arise from different genes and hormones during fetal development, in childhood and adulthood. We discuss what drives male- versus female-specific behaviors and how hormonal fluctuations across the lifespan, including puberty, the menstrual cycle, menopause and aging – affect behavior, cognition and health. Additionally, we discuss how biology relates to gender identity and the impact of hormone therapies on brain circuits that regulate mating, parenting and social bonding.
Read the episode show notes at hubermanlab.com.
Thank you to our sponsors
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Timestamps
00:00:00 Nirao Shah
00:02:11 Mice, Humans & Brain, Biological Conservation
00:05:25 Hormones, Nature vs Nurture
00:07:13 Biological Sex Differences, Chromosomes & SRY Gene, Hormones
00:16:01 Sponsors: Maui Nui & Eight Sleep
00:19:09 Androgen Mutations, Feminization & Masculinization
00:22:04 SRY Gene; Animals & Sexual Trans-Differentiation
00:27:49 Hormones & Biological Brain Differentiation
00:31:22 Congenital Adrenal Hyperplasia, Androstenedione; Stress & Pregnancy
00:35:56 Genes, Brain Differentiation & Sexual Identity; Congenital Adrenal Hyperplasia
00:43:37 Testosterone, Estrogen & Brain Circuits
00:47:27 Sponsors: AG1 & LMNT
00:50:36 Intersex Individuals, Castration
00:52:23 Female Sexual Behavior, Brain, Testosterone & Pheromones
00:57:58 Identify as Heterosexual or Homosexual, Difference in Hormone Levels?
01:00:42 Gender, Sexual Orientation & Hormones; Hormone Replacement Therapy
01:10:21 Aromatization; Steroid Hormones & Gene Expression
01:15:00 Kids & Changing Gender Identity
01:19:05 Sexual Behavior, Refractory Period & Male Brain, Tacr1 Cells
01:21:31 Sponsor: Function
01:23:19 Hypothalamus, Dopamine, Prolactin, Cabergoline, Libido, Dopamine
01:27:05 Brain Circuits, Aggression & Sexual Behavior
01:32:40 Refractory Period; Age, Testosterone & Libido
01:36:07 Tacr1 Cells in Females, Periaqueductal Gray & Innate Behaviors
01:40:00 Parenting Behaviors & Brain Circuits; Pet Dogs
01:43:12 Oxytocin, Pair Bonding, Vasopressin; Biological Redundancy
01:47:22 Libido, Melanocortin, Tacr1 Neurons; GLP-1 Agonists, Clinical Trials; Kisspeptin
01:56:43 Female Brain Changes, Menstrual Cycle, Pregnancy, Menopause; Estrogen; Men & Hormone Fluctuation?
02:04:10 Life Experience Male vs Female, Sex Recognition, Behaviors & Context
02:16:05 Pain Management; Endocrine Disrupters, Gender Identity
02:21:03 Future Projects
02:24:29 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter
Disclaimer & Disclosures
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Huberman Lab
The Huberman Lab podcast is hosted by Andrew Huberman, Ph.D., a neuroscientist and tenured professor in the department of neurobiology, and by courtesy, psychiatry and behavioral sciences at Stanford School of Medicine. The podcast discusses neuroscience and science-based tools, including how our brain and its connections with the organs of our body control our perceptions, our behaviors, and our health, as well as existing and emerging tools for measuring and changing how our nervous system works.
Huberman has made numerous significant contributions to the fields of brain development, brain function, and neural plasticity, which is the ability of our nervous system to rewire and learn new behaviors, skills, and cognitive functioning. He is a McKnight Foundation and Pew Foundation Fellow and was awarded the Cogan Award, given to the scientist making the most significant discoveries in the study of vision, in 2017.
Work from the Huberman Laboratory at Stanford School of Medicine has been published in top journals, including Nature, Science, and Cell, and has been featured in TIME, BBC, Scientific American, Discover, and other top media outlets.
In 2021, Dr. Huberman launched the Huberman Lab podcast. The podcast is frequently ranked in the top 10 of all podcasts globally and is often ranked #1 in the categories of Science, Education, and Health & Fitness.
