Scientific ideas can take a long time to gestate, and their fusion sometimes emerges from the most unexpected of directions. The talk will illustrate a chemist’s attempt to merge ideas from different areas of mathematics, molecular biology, physics and indeed chemistry, and which together span some 314 years of scientific (and indeed musical) development. The central theme concerns twisted objects known as Mobius bands, their molecular analogues, and the consequences of exploring what happens when additional twists are added. The talk will also address the theme of how to express the emerging three dimensional concepts in a visually comprehensible and semantically harvestable manner suitable for both a (re-invention) of the scientific journal for an Internet era, and in presentations to an audience, with the help of some scissors, paper and hopefully the audience itself.