Prednisone is a synthetic corticosteroid derived from cortisol that is either naturally produced in your body or is synthetically man-made. Synthetic corticosteroids are used in people with adrenal glands that are unable to produce adequate amounts naturally. There exist two types of corticosteroids; namely Gluco-corticoids and Mineralo-corticoids. Prednisone is a synthetic gluco-corticoid and it doesn't play nice. And, because it doesn't play nice people desire something that does. Enter Cannabis. People want to know; can you take CBD oil with Prednisone? Do they play nice together or not? And if not, which one's better? Find out in today's episode of the Hemp Nerd podcast.