All content for Healthier World with Quest Diagnostics is the property of Quest Diagnostics and is served directly from their servers
with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
In this special episode of Healthier World designed to give you Instant Insights, we explore a vascular-specific inflammatory marker that can indicate risk for cardiometabolic disease and all-cause mortality—myeloperoxidase. In this episode, we break down the biology and function of MPO, its contribution to vascular inflammation, and its potential as a biomarker of vulnerable soft plaque in the arteries.
This episode will
Define myeloperoxidase (MPO) and describe its biological function (1:20)
Explain the relationship between MPO and vascular inflammation (2:15)
Recognize the role of MPO in cardiometabolic disease (2:55)
Review treatment considerations for elevated MPO (3:45)
The content was current as of the time of recording. To learn more, please review the additional resources below for information on our cardiovascular, metabolic, endocrine, and wellness offerings as well as educational resources and insights from our team of experts. At Quest Diagnostics, we are committed to providing you with results and insights to support your clinical decisions.
Date: 7/2025
Speaker(s): Maeson Latsko, PhD
Contributor(s): Maeson Latsko, PhD; Trisha Winchester, PhD; Millicent Kee, MSN, FNP-BC
Additional Resources
Ordering information:
MPO ordering information
MPO Test Summary
Quest Diagnostics Clinical Education Center [Link]
References:
Iakoubova OA, Haji-Sheikhi F, Louie JZ, et al. Association of MPO levels with cardiometabolic disease stratified by atherosclerotic cardiovascular risk and intensity of therapy in a workforce population. Sci Rep. 2025;15(1):12244. Published 2025 Apr 10. doi:10.1038/s41598-025-89373-7
