We’re not talking about coeliac disease here, which is an autoimmune condition where the immune system overreacts to gluten. Some people experience gut and other symptoms after eating gluten-based or wheat-based foods without a coeliac diagnosis. However a new review suggests some people with this sensitivity could be reacting to something else in the diet, not gluten. Gut symptom study — a world-first international clinical trial comparing two proven treatments for IBS: the low-FODMAP diet and an exposure-based therapy that retrains the gut-brain connection. The study is fully online and open to adults located anywhere in Australia (or the United States) who are currently experiencing gut symptoms (similar to IBS). For listeners interested in learning more about the study or expressing interest, they can go to: gutresearchstudy.com  Guest/s Associate Professor Jess Biesiekierski, head of human nutrition at the University of Melbourne References Non-coeliac gluten sensitivity - the Lancet Global prevalence of self-reported non-coeliac gluten and wheat sensitivity: a systematic review and metaanalysis