In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
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In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
Understanding RBC Parameters: Patterns, Pitfalls, and Clinical Pearls
Haemline
36 minutes
4 months ago
Understanding RBC Parameters: Patterns, Pitfalls, and Clinical Pearls
Red cells: they're not just bags of haemoglobin. In this episode of Haemline, we explore the diagnostic goldmine hiding in those RBC parameters you've possibly been scrolling past. Learn how to interpret red cell count, MCV, RDW, MCH, and MCHC in context—and why their relationships often matter more than the numbers alone. Featuring: cold agglutinins behaving badly, the rule of threes, and why your biomedical scientist deserves more credit. Through real clinical cases, we explore how to disen...
Haemline
In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
