In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
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In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
Reading Between the Cells: Making Sense of WBC Differentials
Haemline
25 minutes
4 months ago
Reading Between the Cells: Making Sense of WBC Differentials
Full blood counts: We all request thousands and glance at them every day. If there’s one test worth understanding inside out, it’s this one. This episode focuses on white cells: how modern analysers generate a differential count, why they throw up so many flags, and when you should pick up the phone. Learn how to interpret automated white cell differentials, when to insist on a blood film, and why a bit of technological insight might save you from the missed diagnosis—or the 3am emergency tha...
Haemline
In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
