In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
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In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
Of Clumps and Counts: Understanding Platelet Parameters
Haemline
19 minutes
4 months ago
Of Clumps and Counts: Understanding Platelet Parameters
Platelets are minuscule, but they cause outsized trouble in the lab and the clinic. From EDTA clumping to cryoglobulin confusion, from giant platelets that escape detection to inherited disorders masquerading as ITP, we explore the curious twists behind every platelet parameter. Join us for a tour of the quirks and pitfalls of platelet counting, why the MPV misleads more than it helps, and how the immature platelet fraction might tell us something useful, if we know how to interpret it. In a ...
Haemline
In double cord blood transplantation, one unit engrafts and the other is rejected—but the losing unit might be doing more than previously imagined. A 2025 Blood Advances study from the Eurocord–EBMT registry reveals how the immunological battle between cord units can be redirected against leukaemia, particularly when the patient and losing unit share the right HLA mismatches. In this episode, we unpack the elegant biology behind this unintended vaccine effect, explore the surprising lack of e...
