Arjun Joshi MD and Joseph Goodman MD discuss advances in oropharyngeal cancer care. They share how the goals of treatment for the patient are protecting vital structures, function and form. They highlight how endoscopic instrumentation coupled with improved imaging and localization techniques are being used to adequately resect tumors with minimum damage to surrounding tissues and how emerging technologies, such as TORS, have allowed surgeons to access hard-to-reach areas of the mouth and throat in the treatment of head and neck cancers.