In this episode, we are joined by Professor Patrick Chinnery. Patrick is a Wellcome Trust Principal Research Fellow at the MRC Mitochondrial Biology Unit at the University of Cambridge, where he is also Professor of Neurology and Head of the Department of Clinical Neurosciences. We chat about the challenges of diagnosing patients with mitochondrial diseases, the power of genomics for diagnosis, and the ins and outs of developing new treatments for rare diseases.