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From First Principles
Lester Nare and Krishna Choudhary
14 episodes
5 days ago
We break down the week’s biggest science headlines from first principles—because understanding the world shouldn’t require a PhD.
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Science
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All content for From First Principles is the property of Lester Nare and Krishna Choudhary and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
We break down the week’s biggest science headlines from first principles—because understanding the world shouldn’t require a PhD.
Show more...
Science
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FFP EP. 3 | Oldest Molecule, Programmable Proteins, Europa Radar & Light’s Double Life
From First Principles
1 hour 16 minutes 46 seconds
2 months ago
FFP EP. 3 | Oldest Molecule, Programmable Proteins, Europa Radar & Light’s Double Life

We go from the universe’s first chemistry to tomorrow’s designer biology, swing by Mars to tune Europa Clipper’s ice radar, and finish with a fresh take on the double-slit experiment.


In this episode

  • The “oldest molecule” puzzle (HeH⁺), cooling the early universe, and why JWST’s findings matter

  • Programmable proteins: reassigning codons, recoding organisms, and real biosafety

  • Europa Clipper’s REASON radar test at Mars: frequencies, ice thickness & ocean clues

  • Double-slit, demystified: single photons, “which-path” info, and measurement reality

Chapters
00:00 Intro

• 01:26 First molecule

• 22:27 Programmable proteins

• 43:05 Europa radar

• 55:00 Double-slit

• 1:15:03 Sign-off

From First Principles
We break down the week’s biggest science headlines from first principles—because understanding the world shouldn’t require a PhD.