023 Depleted: How we are Beginning to Visualize the Tumor Microenvironment

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For Whom the Cell Tolls: Cancer Biology

Prof. Keenan Hartert

27 episodes

6 days ago

Welcome to For Whom the Cell Tolls! This cast explores the fascinating stories of Biology that I've encountered in my journey as a Biology Professor and lymphoma scientist at Minnesota State University and my previous experience at Mayo Clinic. Major themes to be explored include cancer, tumorigenesis, new therapy mechanisms, immunology, life/death, disease ecology, microbiology, and evolution, among others. I try to integrate philosophy, culture, and the arts alongside emerging Biology findings to share the stories of life that I have always loved. Enjoy! https://profkeenanhartert.weebly.com

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023 Depleted: How we are Beginning to Visualize the Tumor Microenvironment

For Whom the Cell Tolls: Cancer Biology

24 minutes 36 seconds

2 years ago

023 Depleted: How we are Beginning to Visualize the Tumor Microenvironment

Welcome back! It's been a while. I'm excited to get going again with an episode on the emerging science of "ecotyping" the cells around tumors - the microenvironment. Ecology and Evolution of lymphoma tumors is only half the story. We needed to know more about the state of cells around the tumor. How do they affect the surrounding immune cells? Do they support the tumor? We examine the worst possible scenario: when very little remains except for tumor and support cells. What are the consequences for immune-specific therapies like CAR-T cells? Hopefully this episode provides a good intro to our new tools to measure the TME and how it can further advance precision cancer medicine. I hope that you enjoy!

Steen: https://pubmed.ncbi.nlm.nih.gov/34597589/

Katlov: https://pubmed.ncbi.nlm.nih.gov/33541860/