
We are joined by Dr Matthew Nagra to dive into animal-free nutrition. We take a dive into conditionally essential amino acids, wound healing, depression, vitamin B12, gut health and debunk a few claims along the way. Let's learn 00:00 Intro 00:43 Are conditionally essential amino acids ever essential ? 03:42 Are vegans at risk of reduced wound healing ? 04:17 How much choline do we need per day ? 05:53 Claim: Aim for 2000 mg of choline per day (Dr Andew Huberman) 07:14 Potential polymorphism for considerations 08:16 Is elevated homocysteine a causal risk factor or a just a marker ? 09:14 Claim: Vegan mothers have a placenta of a smoker (CarnivoreMD) 15:46 Are vegans at risk of depression ? 20:08 Can we train our gut to get used to fibre ? 24:07 How long can you survive without B12 ? 25:37 The Blood Type Diet: Science or Fiction ? 28:12 Facts about Dr Matthew Nagra 32:31 Outro References & Resources Mentioned: Concept of Conditionally Essential Amino Acids https://www.cambridge.org/core/books/abs/neonatal-nutrition-and-metabolism/conditionally-essential-nutrients-choline-inositol-taurine-arginine-glutamine-and-nucleotides/0378571060A6F0EEE8034DDA79CAEFF1 Pregnancy https://link.springer.com/article/10.1007/s00404-020-05689-xhttps://obgyn.onlinelibrary.wiley.com/doi/10.1111/1471-0528.13280https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561836/https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/overall-plantbased-diet-index-during-pregnancy-and-risk-of-gestational-diabetes-mellitus-a-prospective-cohort-study-in-china/B932430D76DCD86FA14C5363AF11893C VeChi Studies https://link.springer.com/article/10.1007/s00394-021-02753-3https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8157583/ Choline Studies https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9303951/https://pubmed.ncbi.nlm.nih.gov/35575618/ Facts on Choline https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/https://www.eatforhealth.gov.au/nutrient-reference-values/nutrients/cholinehttps://pubmed.ncbi.nlm.nih.gov/23193625/https://pubmed.ncbi.nlm.nih.gov/26886842/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637180/ The following paper is where the Choline AI came from: https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.5.7.2010061 Video from Huberman Lab with the claim made on choline https://www.youtube.com/watch?v=E7W4OQfJWdw Vegan sources of choline: https://www.pinterest.ch/pin/474426141997872811/ Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism: epidemiology, metabolism and the associated diseases https://pubmed.ncbi.nlm.nih.gov/25449138/#:~:text=The%20Methylenetetrahydrofolate%20reductase%20(MTHFR)%20C677T,on%20the%20geography%20and%20ethnicity. The Liver King Lie https://www.youtube.com/watch?v=BKpmAGZQetchttps://pubmed.ncbi.nlm.nih.gov/36841216/ Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis https://pubmed.ncbi.nlm.nih.gov/29551598/ Paul Salodino & Liver King talking about selling supplements https://www.youtube.com/watch?v=eLTMuX5wloU
Mental Health & depression https://www.tandfonline.com/doi/epdf/10.1080/10408398.2020.1741505?src=getftr https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466124/ https://academic.oup.com/nutritionreviews/article/80/2/242/6209457?login=true Kevin Klatt thread on choline: https://twitter.com/KCKlatt/status/1626246629941743617?s=20
Gut Health & Fiber https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228670/#:~:text=A%20small%20percentage%20(3%2D11,diets%20without%20flatulence%2Dproducing%20components. https://www.sciencedirect.com/science/article/pii/S0002916522028131?via%3Dihub Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504379/ The Blood Type Diet: Science or Fiction? https://drmatthewnagra.com/the-blood-type-diet-science-or-fiction/ https://pubmed.ncbi.nlm.nih.gov/15229195/ https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084749