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Follow the Gradient
Follow the Gradient
56 episodes
3 days ago
Insider knowledge and real stories about how to build a scaleup in Europe while staying sane. Each week founders Melanie Gabriel and Christian Woese pick for you the latest startup news, dive deep into one specific question on a founder's or startup operator's mind and share how to solve the challenge together with an expert. Follow the Gradient and stay tuned.
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Entrepreneurship
Business
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All content for Follow the Gradient is the property of Follow the Gradient and is served directly from their servers with no modification, redirects, or rehosting. The podcast is not affiliated with or endorsed by Podjoint in any way.
Insider knowledge and real stories about how to build a scaleup in Europe while staying sane. Each week founders Melanie Gabriel and Christian Woese pick for you the latest startup news, dive deep into one specific question on a founder's or startup operator's mind and share how to solve the challenge together with an expert. Follow the Gradient and stay tuned.
Show more...
Entrepreneurship
Business
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From science risk to market fit - Cradle’s Stef van Grieken on building a biotech venture in Europe
Follow the Gradient
38 minutes 30 seconds
4 months ago
From science risk to market fit - Cradle’s Stef van Grieken on building a biotech venture in Europe

Most founders wait until Series A to clean up their cap table. Stef did the opposite - and spent $70K upfront just to get the foundations right.

As co-founder of Cradle, he built a biotech company for global scale from day one: navigating European legal complexity, validating science in skeptical labs, and paying early customers out of pocket to prove it worked.

In this episode, we get into:

  • Why Cradle paid its first two customers—and how that unlocked top-tier pharma clients

  • How to structure your company early to avoid massive headaches later

  • Why European startup culture struggles with ambition—and what needs to change

  • How to hire ML talent in Europe when OpenAI is knocking on the same doors

    🟢 And before you go, subscribe to our free newsletter at ⁠⁠⁠⁠⁠⁠⁠followthegradient.io⁠⁠⁠⁠⁠⁠⁠. Twice a week, we break down startup and tech news, share exclusive insights from our podcast guests, highlight top job openings from European startups, and provide food for thought you won’t find anywhere else. 🟡

Follow the Gradient
Insider knowledge and real stories about how to build a scaleup in Europe while staying sane. Each week founders Melanie Gabriel and Christian Woese pick for you the latest startup news, dive deep into one specific question on a founder's or startup operator's mind and share how to solve the challenge together with an expert. Follow the Gradient and stay tuned.