Dr. Huff is the Chief Medical Informatics Officer at Graphite Health, and a Professor (Clinical) of Biomedical Informatics at the University of Utah. He is board certified in Clinical Pathology.

He has worked in the area of medical vocabularies and medical database architecture for the past 30+ years. He is currently a fellow of the American College of Medical Informatics, a co-chair of the LOINC Committee, and a co-chair of the HL7 Clinical Information Modeling Initiative (CIMI). He is also the Chair of Logica (formerly the Healthcare Services Platform Consortium (HSPC)) and the Chair of the FHIR Foundation.

He is the former CMIO at Intermountain Healthcare, a former member of the ONC HIT Standards Committee and a former member of NCVHS. He is also a previous Chair (twice) of Health Level Seven (HL7). He teaches a course in medical vocabulary and data exchange standards in the Department of Biomedical Informatics at the University of Utah.