Exploring Best Practices for Diagnosis & Management of Adult-Onset Still's Disease
AOSD Podcast
4 episodes
6 days ago
Adult-onset Still’s disease (AOSD) is a rare, polygenic autoinflammatory syndrome with a pathogenesis similar to systemic juvenile inflammatory arthritis. Join Drs. Petros Efthimiou and Olga Petryna as they discuss making the diagnosis of AOSD through interpretation of clinical and laboratory findings and careful exclusion of other diseases. The faculty review the evidence related to the variety of medications often used to treat patients with AOSD, focusing on canakinumab, the only medication approved in the United States for the disease.
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Adult-onset Still’s disease (AOSD) is a rare, polygenic autoinflammatory syndrome with a pathogenesis similar to systemic juvenile inflammatory arthritis. Join Drs. Petros Efthimiou and Olga Petryna as they discuss making the diagnosis of AOSD through interpretation of clinical and laboratory findings and careful exclusion of other diseases. The faculty review the evidence related to the variety of medications often used to treat patients with AOSD, focusing on canakinumab, the only medication approved in the United States for the disease.
Exploring Best Practices for Diagnosis & Management of Adult-Onset Still's Disease
14 minutes 41 seconds
4 years ago
Pathogenesis & Clinical Features
Adult-onset Still’s disease appears to share a similar pathogenesis and disease burden as systemic juvenile inflammatory arthritis
Viral infection appears to be a common trigger in those with a genetic predisposition, resulting in producing a pro-inflammatory state
Patients often present with Still’s triad: daily fevers, evanescent rash, and arthritis
Exploring Best Practices for Diagnosis & Management of Adult-Onset Still's Disease
Adult-onset Still’s disease (AOSD) is a rare, polygenic autoinflammatory syndrome with a pathogenesis similar to systemic juvenile inflammatory arthritis. Join Drs. Petros Efthimiou and Olga Petryna as they discuss making the diagnosis of AOSD through interpretation of clinical and laboratory findings and careful exclusion of other diseases. The faculty review the evidence related to the variety of medications often used to treat patients with AOSD, focusing on canakinumab, the only medication approved in the United States for the disease.
