"There isn't, and it is unlikely there ever will be, a single approach to long COVID. It's very much about personalised medicine." James Chalmers steps away from the ERJ briefly to discuss the recent Monograph on "COVID-19: An Update", which he co-Guest Edited with Catia Cilloniz and Bin Cao. Dorina Esendagli (the Monograph's Early Career Member representative) talks to James about diagnostic tools, diversity in clinical presentation, approaches to treatment, vaccine boosters for new variants, the treatable traits concept and, importantly, the ongoing problem of long COVID.