The Environmental and Energy Study Institute (EESI) held a briefing about climate adaptation, resilience, and mitigation strategies in the Columbia River basin. The Columbia, which winds through British Columbia, Oregon, and Washington state, is an important source of food, drinking water, irrigation, recreation, and clean energy for the Pacific Northwest. However, the effects of climate change have created and exacerbated problems like estuarine habitat loss, toxic algal blooms, low water levels, and diminished fish populations, highlighting the importance of finding science-based solutions to these issues. This briefing also discussed the outcomes of the Uncommon Dialogue, which brought together tribes, national and local government, the hydropower industry, and river conservation stakeholders to identify shared approaches to steward river health and safety while ensuring hydropower operations provide clean, affordable energy. Panelists discussed the role of federal investments in the Columbia River’s resilience and health, including Inflation Reduction Act and Infrastructure Investment and Jobs Act funding.