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Key Moments:
0:00 Introduction
1:12 Journey from Electrical Engineering to Neuroscience
6:45 Initial Interest in Neuroscience
8:16 What is connectomics?
11:45 Parallels Between Microchip Design and Neuroscience
14:22 Probabilistic Reconstruction in Connectomics
19:46 Neurons Behaving Like Brain Regions In C. Elegans
22:17 Incorporating Biological Knowledge into Reconstruction Models and Techniques
25:47 Humans vs ML: Neuron Image Classification
28:05 Future of Connectomics
31:20 Expansion Microscopy
33:19 Genetic Barcoding
34:25 Synchrotrons and X-Rays
34:56 Combining Techniques
35:52 Connectomics: From Flies to Larvae Zebrafish - Optical Microscopy
37:19 Bee Neuroscience, Behavior, and Connectomics
40:03 Mouse Connectomics: Eventually Expansion and Exploration of More Complex Animal Brains
42:39 Any Possibility to Understand the Human Brain at this Level of Detail?
45:07 Tips for Breaking into Connectomics and Neuroscience
50:50 Why are gap junctions hard to see?
53:48 Connectomics Applied to Neuromorphic Computing
55:07 Alcoholic Fruit Flies: Connectomics Applied to Human Medicine
58:03 Conclusion and Contact Info
Dr. Scheffer’s email: LouScheffer@gmail.com
Recorded: 3/20/2024
Host: Robert Murcko
