This podcast episode explores the Autism Data Science Initiative (ADSI), a $50 million program launched by the U.S. National Institutes of Health in 2025, aimed at revolutionizing autism research through the use of big data and artificial intelligence (AI). The initiative aims to integrate genomic, environmental, and clinical datasets to uncover the complex causes of autism and guide more effective, individualized treatments. By leveraging machine learning and advanced analytics, ADSI seeks to identify genetic-environmental interactions, explain the rise in autism prevalence, and match interventions to the unique needs of different patient subgroups. Ultimately, the goal is to move toward precision medicine, accelerating the development of targeted therapies for core symptoms and related conditions. Produced by Dr. Jake Chen.