#75: buprenorphine / naloxone (Suboxone) | Used in the Treatment of Opioid Dependence

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Drug Cards Daily

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5 days ago

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#75: buprenorphine / naloxone (Suboxone) | Used in the Treatment of Opioid Dependence

Drug Cards Daily

9 minutes 29 seconds

2 years ago

#75: buprenorphine / naloxone (Suboxone) | Used in the Treatment of Opioid Dependence

Suboxone is a medication commonly used for the treatment of opioid dependence. It is a combination of two active ingredients: buprenorphine and naloxone. Buprenorphine, a partial opioid agonist, helps reduce cravings and withdrawal symptoms by binding to the same receptors in the brain as opioids but with milder effects. Naloxone, an opioid antagonist, is included to deter misuse of the medication. If Suboxone is crushed or injected, naloxone counteracts the effects of other opioids, precipitating withdrawal symptoms. When taken as directed sublingually (under the tongue), naloxone has minimal bioavailability and does not interfere with the therapeutic effects of buprenorphine. Suboxone is typically prescribed as part of a comprehensive treatment program that includes counseling and psychosocial support. Healthcare professionals play a critical role in managing Suboxone treatment, including patient assessment, monitoring progress, and adjusting dosages as needed. While Suboxone is generally well-tolerated, common side effects include constipation, nausea, headache, insomnia, and sweating. Healthcare professionals should educate patients about potential side effects and provide guidance on managing them. Suboxone, when used in conjunction with a comprehensive treatment approach, can be an effective tool in helping individuals reduce cravings and work towards sustained recovery from opioid dependence.

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