In this episode, Rich and Pip discuss vaccine-induced immune thrombotic thrombocytopenia and heparin-induced thrombocytopenia. They critique a recent paper that has shown that VITT has been around before vaccines against Covid-19. Importantly, they discuss which patients should be tested for spontaneous VITT- and HIT-like syndromes, and discuss a recent case.
The paper is: Schönborn L. et al. Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure. Blood. 2023 Dec 28;142(26):2305-2314.
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In this episode, Rich and Pip discuss vaccine-induced immune thrombotic thrombocytopenia and heparin-induced thrombocytopenia. They critique a recent paper that has shown that VITT has been around before vaccines against Covid-19. Importantly, they discuss which patients should be tested for spontaneous VITT- and HIT-like syndromes, and discuss a recent case.
The paper is: Schönborn L. et al. Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure. Blood. 2023 Dec 28;142(26):2305-2314.
#7 Anticoagulation for AF in end-stage renal failure
Don't Just Read the Guidelines
25 minutes 31 seconds
4 years ago
#7 Anticoagulation for AF in end-stage renal failure
Just me for this episode. I give a short run down of the evidence for anticoagulation for AF in patients with end stage renal failure who are on dialysis.
Here are some links to the articles mentioned in the episode:
1) Randhawa et al (2020). Association Between Use of Warfarin for Atrial Fibrillation and Outcomes Among Patients With End-Stage Renal Disease. A Systematic Review and Meta-analysis https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2763969
2)Siontis et al. (2018) Outcomes Associated With Apixaban Use in Patients With End-Stage Kidney Disease and Atrial Fibrillation in the United States https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.035418
3)Königsbrügge O et al (2019). Atrial fibrillation in patients with end‐stage renal disease on hemodialysis: Magnitude of the problem and new approach to oral anticoagulation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781927/
Don't Just Read the Guidelines
In this episode, Rich and Pip discuss vaccine-induced immune thrombotic thrombocytopenia and heparin-induced thrombocytopenia. They critique a recent paper that has shown that VITT has been around before vaccines against Covid-19. Importantly, they discuss which patients should be tested for spontaneous VITT- and HIT-like syndromes, and discuss a recent case.
The paper is: Schönborn L. et al. Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure. Blood. 2023 Dec 28;142(26):2305-2314.
