For a captioned version or to access the transcript, please visit: https://www.pharmaron.com/knowledge-center/dmpk-insights-12-bbb-transporters/ In this podcast, Elena and Mikko will discuss the current state-of-the-art around transporter sub-types and their expression within the blood-brain barrier (BBB) and opportunities for utilizing these transporters for brain drug delivery. We will address the following questions: Current knowledge of BBB transporters in health and disease&n...
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For a captioned version or to access the transcript, please visit: https://www.pharmaron.com/knowledge-center/dmpk-insights-12-bbb-transporters/ In this podcast, Elena and Mikko will discuss the current state-of-the-art around transporter sub-types and their expression within the blood-brain barrier (BBB) and opportunities for utilizing these transporters for brain drug delivery. We will address the following questions: Current knowledge of BBB transporters in health and disease&n...
DMPK Insights #1: Candidate Survival – 3 Pillars to 5Rs and Beyond
DMPK Insights
45 minutes
1 year ago
DMPK Insights #1: Candidate Survival – 3 Pillars to 5Rs and Beyond
In this podcast, Dr. Paul Morgan, Head of DMPK at Grünenthal Group, discusses the development of the publication that introduced the “5R framework” and improved the likelihood of AstraZeneca candidate survival from candidate drug nomination to Phase III. We will then discuss how the area has developed since then and where the field may go in the future.The episode addresses the following questions:What was the situation like that led to the development of the 5Rs?How was the analysis conducte...
DMPK Insights
For a captioned version or to access the transcript, please visit: https://www.pharmaron.com/knowledge-center/dmpk-insights-12-bbb-transporters/ In this podcast, Elena and Mikko will discuss the current state-of-the-art around transporter sub-types and their expression within the blood-brain barrier (BBB) and opportunities for utilizing these transporters for brain drug delivery. We will address the following questions: Current knowledge of BBB transporters in health and disease&n...