Hani Goodarzi is Quantitative and Computational Biologist, Core Investigator at the Arc Institute, Associate Professor at UCSF, and co-founder of Exai Bio and Vevo Therapeutics. Episode links and chapters below.
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Episode Links:
Chapters:
- (00:00) - Teaser
- (02:12) - Episode Introduction & Preview
- (07:35) - Hani’s Path Into Quantitative and Computational Biology
- (11:55) - The Emerging Promise of Foundation Models Such as Evo 2
- (15:53) - Dry Side vs. Wet Side of Biology
- (22:23) - Pivoting Into AI for Life Science From Unrelated Domains, and the Importance of Culture in Cross-Functional Teams
- (27:28) - How to Develop Multidisciplinary Teams: Brutal Honesty
- (30:07) - How Arc Institute’s Org and Funding Structure Enables Innovative Science
- (36:24) - How Tech Founders Are Pushing Biotech Innovation
- (39:07) - Hani’s Collaboration with NVIDIA and Greg Brockman of OpenAI
- (43:57) - The Science Behind Exai’s Early Cancer Detection Platform
- (52:05) - DNA Methylation to Improve Cancer-Specific Signals From Blood
- (55:25) - UCSF’s Application of This Technology for Breast Cancer Detection
- (58:34) - How Startups Help Bridge the Science “Valley of Death”
- (01:04:24) - Supporting Hani’s Work Through Scientific Contributions, Evangelism, and Applying the Scientific Method Across Disciplines
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