This research article investigates the long-term effects of early-life sugar intake on the development of type 2 diabetes and hypertension. Utilising a natural experiment from the end of sugar rationing in the UK in 1953, the study compares adults with varying levels of sugar exposure during their first 1000 days. The findings suggest that restricted sugar intake in early life significantly reduced the risk and delayed the onset of both conditions. This highlights the critical impact of early nutrition on lifelong metabolic health, with in-utero sugar restriction also showing a protective effect.
Review paper:
Gracner T, Boone C, Gertler PJ. Exposure to sugar rationing in the first 1000 days of life protected against chronic disease. Science. 2024 Nov 29;386(6725):1043-1048.
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